https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Maternal undernutrition around the time of conception and embryo number each impact on the abundance of key regulators of cardiac growth and metabolism in the fetal sheep heart https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19577 Sat 24 Mar 2018 07:58:20 AEDT ]]> Maternal undernutrition during the first week after conception results in decreased expression of glucocorticoid receptor mRNA in the absence of GR exon 1₇ hypermethylation in the fetal pituitary in late gestation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19576 Sat 24 Mar 2018 07:58:20 AEDT ]]> Effect of periconceptional nutrition on the growth, behaviour and survival of the neonatal lamb https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26513 0.05) but low PCN decreased the size of the neonate (crown-rump-length and metacarpal length P< 0.05). A subset of lambs euthanased at 5 days of age further showed that low PCN decreased the amount of peri-renal fat (P < 0.05) and increased liver mass (P < 0.05) while high PCN increased neck thymus and ovary mass (P < 0.05). Neonatal lambs from low PCN ewes returned faster to their mothers after release (P < 0.05) and contacted the udder in the shortest time (P < 0.05). Significant interactions between PCN treatment and sex (P < 0.05) and between PCN treatment and ewe age (P < 0.05) were also observed for time lambs took to follow the ewe. Survival of lambs was similar but potential differences may have been masked by favourable weather conditions. In conclusion, this study provides evidence of significant changes in lamb growth and development dependent on PCN and, for the first time, links these changes with significant changes in behaviour of the neonate. The impact of these effects on lamb survival and potential reproductive capacity of female offspring remains to be determined.]]> Sat 24 Mar 2018 07:35:32 AEDT ]]>